HOOKIPA PHARMA INC.

(Name of Issuer)

Common Stock, par value $0.0001 per share

(Title of Class of Securities)

43906K 100

(CUSIP Number)

March 24, 2022

(Date of Event Which Requires Filing of this Statement)

	☐	Rule 13d-1(b)
	☒	Rule 13d-1(c)
	☐	Rule 13d-1(d)

CUSIP NO.

43906K 100

                  

1	NAMES OF REPORTING PERSONS
	Gilead Sciences, Inc.
2	CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP (SEE INSTRUCTIONS)
	(a) ☐
	(b) ☐
3	SEC USE ONLY
4	CITIZENSHIP OR PLACE OF ORGANIZATION
	State of Delaware
NUMBER OF SHARES BENEFICIALLY OWNED BY EACH REPORTING PERSON WITH:	5	SOLE VOTING POWER
		3,759,465
	6	SHARED VOTING POWER
		-0-
	7	SOLE DISPOSITIVE POWER
		3,759,465
	8	SHARED DISPOSITIVE POWER
		-0-
9	AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON
	3,759,465
10	CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES ☐
11	PERCENT OF CLASS REPRESENTED BY AMOUNT IN ROW (9)
	7.2%1
12	TYPE OF REPORTING PERSON*
	CO

Item 1(a)	Name of Issuer:
	The name of the issuer is HOOKIPA Pharma Inc. (the “Issuer”).
Item 1(b)	Address of Issuer's Principal Executive Offices:
	The Issuer’s principal executive offices are located at 350 Fifth Avenue, 72nd Floor, Suite 7240, New York, NY 10118.
Item 2(a)	Name of Person Filing:
	This Amendment No. 4 to Schedule 13G is being filed by Gilead Sciences, Inc. (the “Reporting Person”).
Item 2(b)	Address of Principal Business Office or, if none, Residence:
	The address of the principal business office of the Reporting Person is 333 Lakeside Drive, Foster City, California, 94404.
Item 2(c)	Citizenship:
	The Reporting Person is incorporated in the State of Delaware.
Item 2(d)	Title of Class of Securities:
	Common Stock, par value $0.0001 per share
Item 2(e)	CUSIP No.:
	43906K 100
Item 3	If this statement is filed pursuant to Rules 13d-1(b), or 13d-2(b), check whether the person filing is a:
	Not applicable.

	(a)		Amount beneficially owned: 3,759,465
	(b)		Percent of class:  7.2%2
	(c)		Number of shares as to which such person has:
			(i)		Sole power to vote or direct the vote:  3,759,465
			(ii)		Shared power to vote or direct the vote: -0-
			(iii)		Sole power to dispose or direct the disposition:  3,759,465
			(iv)		Shared power to dispose or direct the disposition: -0-

Item 5	Ownership of Five Percent or Less of a Class:
	If this statement is being filed to report the fact that as of the date hereof the reporting person has ceased to be the beneficial owner of more than five percent of the class of securities, check the following ☐.
Item 6	Ownership of More Than Five Percent on Behalf of Another Person:
	Not applicable.
Item 7	Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person:
	Not applicable.
Item 8	Identification and Classification of Members of the Group:
	Not applicable.
Item 9	Notice of Dissolution of Group:
	Not applicable.
Item 10	Certification:
	By signing below, I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under § 240.14a-11.