* | The remainder of this cover page shall be filled out for a reporting person’s initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. |
(1) | Names of reporting persons Takeda Pharmaceutical Company Limited | |||||||||||||||||||
(2) | Check the appropriate box if a member of a group (see instructions) (a) ☐ (b) ☐ | |||||||||||||||||||
(3) | SEC use only | |||||||||||||||||||
(4) | Citizenship or place of organization Japan | |||||||||||||||||||
Number of shares beneficially owned by each reporting person with: | (5) | Sole voting power 0 | ||||||||||||||||||
(6) | Shared voting power 290,693 | |||||||||||||||||||
(7) | Sole dispositive power 0 | |||||||||||||||||||
(8) | Shared dispositive power 290,693 | |||||||||||||||||||
(9) | Aggregate amount beneficially owned by each reporting person 290,693(1) | |||||||||||||||||||
(10) | Check if the aggregate amount in Row (9) excludes certain shares (see instructions) ☐ | |||||||||||||||||||
(11) | Percent of class represented by amount in Row (9) 1.1%(2) | |||||||||||||||||||
(12) | Type of reporting person (see instructions) CO |
(1) | Takeda Pharmaceutical Company Limited’s beneficial ownership of the issuer’s Common Stock is comprised of 290,693 shares of Common Stock held by Takeda Ventures, Inc., a wholly-owned indirect subsidiary of Takeda Pharmaceutical Company Limited. Takeda Ventures, Inc. is owned directly by Takeda Pharmaceuticals U.S.A., Inc., which is owned directly by Takeda Pharmaceutical Company Limited and Takeda Pharmaceuticals International AG. Takeda Pharmaceuticals International AG is a wholly-owned direct subsidiary of Takeda Pharmaceutical Company Limited. |
(2) | Based on 26,072,989 shares of Common Stock outstanding as of August 5, 2021, as reported in the issuer’s Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on August 12, 2021 (“Form 10-Q”). |
(1) | Names of reporting persons Takeda Pharmaceuticals International AG | |||||||||||||||||||
(2) | Check the appropriate box if a member of a group (see instructions) (a) ☐ (b) ☐ | |||||||||||||||||||
(3) | SEC use only | |||||||||||||||||||
(4) | Citizenship or place of organization Switzerland | |||||||||||||||||||
Number of shares beneficially owned by each reporting person with: | (5) | Sole voting power 0 | ||||||||||||||||||
(6) | Shared voting power 79,359(1) | |||||||||||||||||||
(7) | Sole dispositive power 0 | |||||||||||||||||||
(8) | Shared dispositive power 79,359(1) | |||||||||||||||||||
(9) | Aggregate amount beneficially owned by each reporting person 79,359(1) | |||||||||||||||||||
(10) | Check if the aggregate amount in Row (9) excludes certain shares (see instructions) ☐ | |||||||||||||||||||
(11) | Percent of class represented by amount in Row (9) .3%(2) | |||||||||||||||||||
(12) | Type of reporting person (see instructions) CO |
(1) | Takeda Pharmaceuticals International AG’s beneficial ownership of the issuer’s Common Stock is comprised of 79,359 of the 290,693 shares of Common Stock held by Takeda Ventures, Inc., an indirect subsidiary of Takeda Pharmaceuticals International AG. | ||||
(2) | Based on 26,072,989 shares of Common Stock outstanding as of August 5, 2021, as reported in the issuer’s Form 10-Q. |
(1) | Names of reporting persons Takeda Pharmaceuticals U.S.A., Inc. | |||||||||||||||||||
(2) | Check the appropriate box if a member of a group (see instructions) (a) ☐ (b) ☐ | |||||||||||||||||||
(3) | SEC use only | |||||||||||||||||||
(4) | Citizenship or place of organization United States | |||||||||||||||||||
Number of shares beneficially owned by each reporting person with: | (5) | Sole voting power 0 | ||||||||||||||||||
(6) | Shared voting power 290,693 | |||||||||||||||||||
(7) | Sole dispositive power 0 | |||||||||||||||||||
(8) | Shared dispositive power 290,693 | |||||||||||||||||||
(9) | Aggregate amount beneficially owned by each reporting person 290,693(1) | |||||||||||||||||||
(10) | Check if the aggregate amount in Row (9) excludes certain shares (see instructions) ☐ | |||||||||||||||||||
(11) | Percent of class represented by amount in Row (9) 1.1%(2) | |||||||||||||||||||
(12) | Type of reporting person (see instructions) CO |
(1) | Takeda Pharmaceuticals U.S.A., Inc.’s beneficial ownership of the issuer’s Common Stock is comprised of 290,693 shares of Common Stock held by Takeda Ventures, Inc., a wholly-owned direct subsidiary of Takeda Pharmaceuticals U.S.A. | ||||
(2) | Based on 26,072,989 shares of Common Stock outstanding as of August 5, 2021, as reported in the issuer’s Form 10-Q. |
(1) | Names of reporting persons Takeda Ventures, Inc. | |||||||||||||||||||
(2) | Check the appropriate box if a member of a group (see instructions) (a) ☐ (b) ☐ | |||||||||||||||||||
(3) | SEC use only | |||||||||||||||||||
(4) | Citizenship or place of organization United States | |||||||||||||||||||
Number of shares beneficially owned by each reporting person with: | (5) | Sole voting power 0 | ||||||||||||||||||
(6) | Shared voting power 290,693 | |||||||||||||||||||
(7) | Sole dispositive power 0 | |||||||||||||||||||
(8) | Shared dispositive power 290,693 | |||||||||||||||||||
(9) | Aggregate amount beneficially owned by each reporting person 290,693 | |||||||||||||||||||
(10) | Check if the aggregate amount in Row (9) excludes certain shares (see instructions) ☐ | |||||||||||||||||||
(11) | Percent of class represented by amount in Row (9) 1.1%(1) | |||||||||||||||||||
(12) | Type of reporting person (see instructions) CO |
(1) | Based on 26,072,989 shares of Common Stock outstanding as of August 5, 2021, as reported in the issuer’s Form 10-Q. |
Item 1(a) | Name of issuer: |
Item 1(b) | Address of issuer’s principal executive offices: |
Item 2(a) | Name of person filing: |
Item 2(b) | Address of principal business office or, if none, residence: |
Item 2(c) | Citizenship: |
Item 2(d) | Title of class of securities: |
Item 2(e) | CUSIP No.: |
Item 3. | If this statement is filed pursuant to §§240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a: |
Item 4. | Ownership |
Item 5. | Ownership of 5 Percent or Less of a Class. |
Item 6. | Ownership of More than 5 Percent on Behalf of Another Person. |
Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person. |
Item 8. | Identification and Classification of Members of the Group. |
Item 9. | Notice of Dissolution of Group. |
Item 10. | Certifications |
TAKEDA PHARMACEUTICAL COMPANY LIMITED | ||||||||||||||
By | /s/ Paul Sundberg | |||||||||||||
Name: | Paul Sundberg | |||||||||||||
Title: | Authorized Signatory |
TAKEDA PHARMACEUTICALS INTERNATIONAL AG | ||||||||||||||
By | /s/ Paul Sundberg | |||||||||||||
Name: | Paul Sundberg | |||||||||||||
Title: | Authorized Signatory |
TAKEDA PHARMACEUTICALS U.S.A., INC. | ||||||||||||||
By | /s/ Paul Sundberg | |||||||||||||
Name: | Paul Sundberg | |||||||||||||
Title: | Assistant Secretary |
TAKEDA VENTURES, INC. | ||||||||||||||
By | /s/ Paul Sundberg | |||||||||||||
Name: | Paul Sundberg | |||||||||||||
Title: | Assistant Secretary |
Exhibit 99.1 | |||||||||||
Exhibit 99.2 |
TAKEDA PHARMACEUTICAL COMPANY LIMITED | ||||||||||||||
By | /s/ Andrew S. Plump | |||||||||||||
Name: | Andrew S. Plump | |||||||||||||
Title: | Director and Chief Medical & Scientific Officer |
TAKEDA PHARMACEUTICALS INTERNATIONAL AG | ||||||||||||||
By | /s/ Andrea Ferrari | |||||||||||||
Name: | Andrea Ferrari | |||||||||||||
Title: | Director and Secretary |
TAKEDA PHARMACEUTICALS U.S.A., INC. | ||||||||||||||
By | /s/ Paul Sundberg | |||||||||||||
Name: | Paul Sundberg | |||||||||||||
Title: | Assistant Secretary |
TAKEDA VENTURES, INC. | ||||||||||||||
By | /s/ Michael Martin | |||||||||||||
Name: | Michael Martin | |||||||||||||
Title: | President |